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Home Species Homo sapiens
Stomach Cancer

Basic Information

Homo sapiens / Stomach Cancer
Species: Human
Category: Human Cancer Studies
Description: Gastric cancer (GC) is one of the most common malignancies worldwide and it is the fourth leading cause of cancer-related death. GC is a multifactorial disease, where both environmental and genetic factors can have an impact on its occurrence and development. More than 90% of the tumors are adenocarcinomas. The prognosis is dismal, with an average 5-year survival rate of less than 20%, mainly because of late diagnosis, because the early stages are clinically silent. If the tumor is detected and treated before it invades the muscular layer of the stomach, the 5-year survival rate can reach 90%.

Gene Summary

MicroRNA

ICG00153-36
miR-16 miR-93

mRNA

ICG00153-37
B2M GAPDH RPL29
ICG00153-16
HPRT1 18S rRNA B2M GAPDH RPL29

Studies (3)

ICG00153-16

Stomach Cancer
Cell Types
Cancer Studies

Internal Control Genes

Gene Symbol Gene Model Application Scenario Accession Number Primers(5' - 3')
(Forward/Reverse)		 Size (bp) Annealing Temperature Detection
HPRT1 Hypoxanthine Phosphoribosyltransferase
Stomach Cancer Tissues
Matched Normal Tissues
Tumor-Normal Pairs
 NM_000194
F: AGACTTTGCTTTCCTTGGTCAG
R: TCAAGGGCATATCCTACAACAA
 151 58 SYBR
18S rRNA 18S Ribosomal RNA
Stomach Cancer Tissues
Matched Normal Tissues
Tumor-Normal Pairs
 NR_003286
F: GTAACCCGTTGAACCCCATT
R: CCATCCAATCGGTAGTAGCG
 151 58 SYBR
B2M Microglobulin
Stomach Tumor
Snu-216 Cell Line
Snu-638 Cell Line
Snu-719 Cell Line
Ags Cell Line
Mkn-28 Cell Line
Katoiii Cell Line
Jimt1 Cell Line
Non-Stomach Cancer
Snu-C5 Cell Line
A549 Cell Line
U87 Cell Line
Normal Human Hdf Cell Line
Normal Human Hmec Cell Line
 NM_004048
F: ACTGAATTCACCCCCACTGA
R: CCTCCATGATGCTGCTTACA
 114 58 SYBR
GAPDH Glyceraldehyde-3-Phosphate Dehydrogenase
Stomach Tumor
Snu-216 Cell Line
Snu-638 Cell Line
Snu-719 Cell Line
Ags Cell Line
Mkn-28 Cell Line
Katoiii Cell Line
Jimt1 Cell Line
Non-Stomach Cancer
Snu-C5 Cell Line
A549 Cell Line
U87 Cell Line
Normal Human Hdf Cell Line
Normal Human Hmec Cell Line
 NM_002046
F: TGCACCACCAACTGCTTA
R: GGATGCAGGGATGATGTTC
 177 58 SYBR
RPL29 Ribosomal Protein L29
Stomach Tumor
Snu-216 Cell Line
Snu-638 Cell Line
Snu-719 Cell Line
Ags Cell Line
Mkn-28 Cell Line
Katoiii Cell Line
Jimt1 Cell Line
Non-Stomach Cancer
Snu-C5 Cell Line
A549 Cell Line
U87 Cell Line
Normal Human Hdf Cell Line
Normal Human Hmec Cell Line
 NM_000992
F: GGCGTTGTTGACCCTATTTC
R: GTGTGTGGTGTGGTTCTTGG
 120 58 SYBR

Molecular Types:

mRNA

Evaluation Methods

geNorm
NormFinder

Contact

Name: Sung-Ho Goh
Email: andrea@ncc.re.kr
Institution: Research institute, National Cancer Center, 809 Madu-dong, Goyang, Gyeonggi-do 410-769, Republic of Korea

Reference

Identification of valid reference genes for gene expression studies of human stomach cancer by reverse transcription-qPCR.
Rho HW, Lee BC, Choi ES, Choi IJ, Lee YS, Goh SH.
BMC cancer. 2010-05-28

ICG00153-36

Stomach Cancer
Blood Samples
Cancer Studies

Internal Control Genes

Gene Symbol Gene Model Application Scenario Accession Number Primers(5' - 3')
(Forward/Reverse)		 Size (bp) Annealing Temperature Detection
miR-16 MiRNA
Gastric Cancer Patients
Healthy Controls
Serum
Plasma
Tumor-Normal Pairs
 MIMAT0000093
F: Please contact with the researchers for details.
R: Please contact with the researchers for details.
 - 60 SYBR
miR-93 MiRNA
Gastric Cancer Patients
Healthy Controls
Serum
Plasma
Tumor-Normal Pairs
 MIMAT0000069
F: Please contact with the researchers for details.
R: Please contact with the researchers for details.
 - 60 SYBR

Molecular Types:

MicroRNA

Evaluation Methods

geNorm
NormFinder
BestKeeper

Contact

Name: Zhongtao Zhang
Email: zhangzht@medmail.com.cn
Institution: Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, 95 Yongan Road, Xuanwu District, Beijing 100050, People’s Republic of China

Reference

Identification of suitable reference genes for qPCR analysis of serum microRNA in gastric cancer patients.
Song J, Bai Z, Han W, Zhang J, Meng H, Bi J, Ma X, Han S, Zhang Z.
Digestive diseases and sciences. 2011-12-25

ICG00153-37

Stomach Cancer
Cell Types
Cancer Studies

Internal Control Genes

Gene Symbol Gene Model Application Scenario Accession Number Primers(5' - 3')
(Forward/Reverse)		 Size (bp) Annealing Temperature Detection
B2M Microglobulin
Stomach Cancer
Snu-216 Cell Line
Snu-638 Cell Line
Snu-719 Cell Line
Ags Cell Line
Mkn-28 Cell Line
Katoiii Cell Line
Tumor Stomach Tissue
Normal Stomach Tissue
Tumor-Normal Pairs
 NM_004048
F: ACTGAATTCACCCCCACTGA
R: CCTCCATGATGCTGCTTACA
 114 58 SYBR
GAPDH Glyceraldehyde-3-Phosphate Dehydrogenase
Stomach Cancer
Snu-216 Cell Line
Snu-638 Cell Line
Snu-719 Cell Line
Ags Cell Line
Mkn-28 Cell Line
Katoiii Cell Line
Tumor Stomach Tissue
Normal Stomach Tissue
Tumor-Normal Pairs
 NM_002046
F: TGCACCACCAACTGCTTA
R: GGATGCAGGGATGATGTTC
 177 58 SYBR
RPL29 Ribosomal Protein L29
Tumor Stomach Tissue
Normal Stomach Tissue
Tumor-Normal Pairs
 NM_00992
F: GGCGTTGTTGACCCTATTTC
R: GTGTGTGGTGTGGTTCTTGG
 120 58 SYBR

Molecular Types:

mRNA

Evaluation Methods

geNorm
NormFinder

Contact

Name: Sung-Ho Goh
Email: andrea@ncc.re.kr
Institution: Research institute, National Cancer Center, 809 Madu-dong, Goyang, Gyeonggi-do 410-769, Republic of Korea

Reference

Identification of valid reference genes for gene expression studies of human stomach cancer by reverse transcription-qPCR.
Rho HW, Lee BC, Choi ES, Choi IJ, Lee YS, Goh SH.
BMC cancer. 2010-05-28